Yes, you can connect an HD-DVD burner such as the Toshiba 802A 5.25 inch with this power supply unit, as it has a 4-pin Molex connection. The output current of 1500 mA at 12 V is sufficient to operate such a burner.
I don't know the power consumption of these fans. However, if you do not use PWM fan control, it is not worth using such fans. If you use the non-PWM fans, it should work anyway. (Assume the PWM have the same power consumption).