I don't understand this question - I bought this as an enclosure with a hard drive. It has no (visible) screws at all. You would have to destroy the enclosure... Isn't it better to buy a 2.5 hard drive without an enclosure, like Seagate BarraCuda (5TB, 2.5") ?
The only screw is under the label. Shouldn't be opened because of the warranty. I took x-ray pictures of it. Internal connection is SATA, the hard drive is 15mm thick. The pictures are here: https://www.dropbox.com/sh...