Question about Seagate IronWolf

In principle, there is nothing to be said against it. However, NAS hard drives are designed for continuous operation. This means they run with lower revolutions, which is easier on them and advantageous from a heat point of view (the power consumption is also somewhat lower). The disadvantage of the lower rotations is that you have clear performance losses.
So if you only want to use them as data storage, why not.
But if you want to use it as system storage, I recommend a desktop hard drive or, if possible, an SSD.