The lens is designed for full-frame sensors, but can also be used with a Canon R50 with an APS-C sensor. The effective focal length is increased due to the crop factor.
The RF 100-400mm f/5.6-8 IS USM lens is compatible with the Canon EOS R50. Although this lens is designed for full-frame cameras, the R50 also uses the RF mount, making it possible to use this lens without any problems.
The Canon EOS R50 is an APS-C sensor camera, but it is compatible with all RF lenses, including those designed for full-frame formats. This means you can take advantage of the versatility and reach of this lens for nature photography or events such as air shows.