Question about ASUS H81m-Plus, Matx, Lga1150

no, you need a lga 1155 socket for the i5 2500. however, i recommend that you also change the cpu once the board is out. it is already getting on in years and will no longer deliver the absolute top performance for gaming. now is also a good time to upgrade. my recommendation would be a ryzen 1600 with b350 board and 16gb ram. if the money is not enough, a ryzen 2200g +b350 board and 16gb ram would be the optimum. because the cpu can still be upgraded until 2020 without having to change the board.