Question about OWC Akitio Node Titan

The box works via a Thunderbolt 3 connection, which offers bandwidth of up to 40 Gb/s. USB4 incorporates Thunderbolt 3 technology, so in theory it is compatible with USB4. However, no specific information explicitly confirms jitter-free operation on USB4. Correct operation will also depend on the compatibility of the host system, the drivers and the PCIe card used. In short, it should work well on USB4, but there is no formal guarantee that it will be completely jerk-free.