No, the pen does not support pressure sensitivity, so the stroke width does not vary depending on the pressure applied. However, the tilt detection works and dynamically adjusts the stroke width. It is compatible with the iPad 11th generation from 2025 and works in apps such as Affinity Photo and Affinity Designer via iPadOS functions such as tilt and palm detection.
iPad Air
iPad Air (5th generation)
Model: A2588, A2589, A2591
iPad Air (4th generation)
Model: A2316, A2324, A2325, A2072
iPad Air (3rd generation)
Model: A2152, A2123, A2153, A2154
According to the Logitech website. So probably no.