Really depends on the game...most AAA games would likely struggle, but most everything else should be fine...for comparison, this mac is much more powerful than a Nintendo Switch, for example.
Inches do not play a role at all. What matters is the resolution. At my brother's place, I have 2 monitors of 2560x1440 each. So from that point of view, no problem. The Mac can drive a third monitor, but I can't guarantee whether it would manage 2560x1440 again.